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Case study effects of microgravity on the circulatory system

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. It has been described that microgravity affects cellular and molecular structures. Cell membrane, cytoskeleton, cytoplasm and nucleus have been found to be sensible to gravitational changes. Alterations in the male and female reproductive systems have also been reported in mouse and other animals.
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Microgravity and the respiratory system

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The effect of spaceflight and microgravity on the human brain | SpringerLink

The structure of the lung, with its delicate network of airspaces and capillaries, means that gravity has a profound influence on its function. Studies of lung function in the absence of gravity provide valuable insight into how, for we Earth-bound individuals, its unavoidable effects shape our lung function. Gravity causes uneven ventilation in the lung through the deformation of lung tissue the so-called Slinky effect , and uneven perfusion through a combination of the Slinky effect and the zone model of pulmonary perfusion. Both ventilation and perfusion exhibit persisting heterogeneity in microgravity, indicating important other mechanisms.
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The effect of spaceflight and microgravity on the human brain

Frozen sperm samples can remain viable after exposure to microgravity conditions that are somewhat similar to those found in space, new research reveals. The findings, which were presented today June 24 at the European Society of Human Reproduction and Embryology in Vienna, suggest that at least one obstacle on the path towards space-based reproduction may not be insurmountable. However, the study doesn't actually demonstrate how sperm would fare in space, and even if they did, we are still light-years away from making space babies using frozen sperm, one expert told Live Science. Sex in space would be difficult and dangerous for a lot of reasons.
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Space is a harsh environment that affects the body in many ways. In microgravity, bone loss occurs at a rate of 1 to 1. Decreases in bone density and strength are more pronounced in some skeletal regions, such as the pelvis, although much of the loss is reversible upon return to Earth.
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